Glucose Metabolism: A Sweet Relief of Alzheimer’s Disease
نویسندگان
چکیده
Patients and individuals at risk for Alzheimer's disease show reduced glucose metabolism in the brain. A new study takes advantage of a fly model of Alzheimer's disease to demonstrate that enhancing glucose uptake in neurons has strong neuroprotective effects involving improved proteostasis.
منابع مشابه
Detection of Alzheimer\\\\\\\'s Disease using Multitracer Positron Emission Tomography Imaging
Alzheimer's disease is characterized by impaired glucose metabolism and demonstration of amyloid plaques. Individual positron emission tomography tracers may reveal specific signs of pathology that is not readily apparent on inspection of another one. Combination of multitracer positron emission tomography imaging yields promising results. In this paper, 57 Alzheimer's disease neuroimaging ini...
متن کاملMitochondrial Dysfunction in Alzheimer’s Disease and the Rationale for Bioenergetics Based Therapies
Alzheimer's disease (AD) is a debilitating neurodegenerative disorder characterized by the progressive loss of cholinergic neurons, leading to the onset of severe behavioral, motor and cognitive impairments. It is a pressing public health problem with no effective treatment. Existing therapies only provide symptomatic relief without being able to prevent, stop or reverse the pathologic process....
متن کاملSHORT REPORT Hypofunction in the posterior cingulate gyrus correlates with disorientation for time and place in Alzheimer’s disease
The relation between orientation for time and place and regional cerebral glucose metabolism was examined in 86 patients with probable Alzheimer’s disease of minimal to moderate severity. Regional glucose metabolic rates in the posterior cingulate gyri and in the right middle temporal gyrus were significantly correlated with temporal orientation, and the glucose metabolic rate in the right post...
متن کاملCan coconut oil treat Alzheimer’s disease? An honest look at the evidence
The narcotic that shows promise How the body’s back-up fuel source could lead us to the cure The reason coconut oil stands out What the current research can tell us What is Alzheimer’s disease? Alzheimer’s disease is the most common form of dementia worldwide. Those with the disease have decreased ability to use glucose in the brain, which is the primary fuel source for brain cells. As a result...
متن کاملAn alternative approach to the treatment of Alzheimer’s disease
William R Ware, PhD Faculty of Science University of Western Ontario London, Ontario, Canada [email protected] If one takes a realistic view, modern medicine appears to have little of real significant to offer patients with Alzheimer’s disease. Treatments are symptomatic and do not significantly decelerate or prevent progression. Behavioural and psychiatric challenges of great concern to caregi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Current Biology
دوره 26 شماره
صفحات -
تاریخ انتشار 2016